Deamidated Gliadin Peptide (DGP) Antibody, IgA

Deamidated Gliadin Peptide (DGP) Antibody, IgG

Ordering Recommendation

Acceptable single screening test for celiac disease. IgA testing recommended to identify IgA deficiency. Use IgG test in individuals who are IgA deficient. May be useful in diagnosing children <2 years who test negative for tTG and EMA antibodies. May aid in monitoring adherence to gluten-free diet. Celiac Disease Reflexive Cascade (2008114) or Tissue Transglutaminase (tTG) Antibody, IgG (0056009) is the preferred test for screening patients with suspected celiac disease.

Mnemonic

Methodology

Semi-Quantitative Enzyme-Linked Immunosorbent Assay

Performed

Mon-Sat

Reported

1-2 Days

New York DOH Approval Status

This test is New York DOH approved.

Specimen Required

Patient Preparation:

Collect:

Serum separator tube (SST).

Specimen Preparation:

Separate serum from cells ASAP or within 2 hours of collection. Transport 0.5 mL serum. (Min: 0.3 mL)

Storage/Transport Temperature:

Refrigerated

Unacceptable Conditions:

Plasma or other body fluids. Contaminated, hemolyzed, grossly icteric, or grossly lipemic specimens.

Remarks:

Stability:

After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year

Reference Interval

19 Units or less

20-30 Units

Negative

Weak Positive

31 Units or greater

Positive

Interpretive Data

Note

CPT Code

86258

Components

Component Chart Name

Deamidated Gliadin Peptide (DGP) Ab, IgG

Component Test Code

0051359

LOINC

63459-2

Aliases

Celiac Disease Antibodies
Deamidated Gliadin Antibodies (DGP)

Deaminated Gliadin Peptide Antibodies

DGP

DGP Ab

DGP IgA